Down-hearted is a feeling of sadness or depression, and there are several synonyms for this word. Depressed, dejected, despondent, low-spirited, disheartened, and crestfallen are some of the synonyms that can be used interchangeably with down-hearted. Each of these synonyms conveys a sense of sadness in a different way, with depressed indicating a long-standing sadness, despondent indicating a loss of hope, and dejected indicating a feeling of utter disappointment. Low-spirited means dejected or depressed in mood, and disheartened helps to describe a sense of discouragement or a feeling of disillusionment. Crestfallen means the sense of disappointment or dejection, and all of these synonyms can be used to describe the state of feeling down-hearted.