Click chemistry is a term used to describe a type of chemical reaction that is efficient, modular, and highly selective. It involves the formation of covalent bonds between small molecules in a single step and can be used to create a wide range of structures with ease. Some synonyms for click chemistry include "chirality-assisted," "catalytic," "ligand-accelerated," "high-throughput," and "bioorthogonal." Techniques such as copper-catalyzed azide-alkyne cycloaddition (CuAAC), strain-promoted alkyne-azide cycloaddition (SPAAC), and tetrazine-click chemistry are just a few examples of click chemistry methods that have been developed over the years. These techniques have made it possible to quickly and reliably build complex molecular structures for a variety of applications in chemistry, biology, and medicine.