Losing reason or rationality is a common problem, especially when we are in a difficult or stressful situation. Some of the synonyms for the phrase "lose reason" include losing your mind, losing your head, going crazy, or becoming irrational. When we lose reason, we are unable to think logically, we may forget important details, and our behavior becomes erratic and unpredictable. It is essential to control our emotions and stay calm to avoid losing reason. Yoga, meditation, and mindfulness practices can help us stay centered and focused, allowing us to think more clearly and rationally. Taking a break, talking with a trusted person, or seeking professional help can also be beneficial in regaining our reason.